Back to All Subjects
Computational Biology & Molecular Modeling5 Structured Units

Bioinformatics & Molecular Modeling

Sequence analysis, macromolecular structure visualization, molecular docking, and pharmacogenomics workflows.

Unit IUpcoming Curriculum

Introduction to Bioinformatics & Biological Databases

Overview of biological data, NCBI, GenBank, UniProt, Protein Data Bank (PDB), ChEMBL, and accessing biological databases programmatically.

Planned Topics:
Biological Sequence Databanks (NCBI, UniProt)
PDB 3D Macromolecular Structure Formats
ChEMBL & PubChem Bioactivity Repositories
REST APIs for Biological Data Retrieval
Unit NotesContent in Roadmap

Syllabus units ready. Detailed materials will be published soon.

Unit IIUpcoming Curriculum

Sequence Analysis with Biopython

Parsing FASTA and GenBank files, DNA transcription and translation in Python, pairwise and multiple sequence alignment algorithms (Needleman-Wunsch, Smith-Waterman, BLAST).

Planned Topics:
Biopython `Seq` & `SeqRecord` Objects
Automated DNA/RNA Translation
Global vs Local Pairwise Alignment
Running & Parsing Online BLAST via Python
Unit NotesContent in Roadmap

Syllabus units ready. Detailed materials will be published soon.

Unit IIIUpcoming Curriculum

Protein Structure & Molecular Visualization

Analyzing PDB files, secondary structure determination, Ramachandran plot analysis, and programmatic molecular rendering with PyMOL and NGLview in Python.

Planned Topics:
PDB File Architecture (ATOM, HETATM, CONECT)
Ramachandran Plot Generation
3D Interactive Protein Rendering (NGLview)
Binding Pocket & Active Site Identification
Unit NotesContent in Roadmap

Syllabus units ready. Detailed materials will be published soon.

Unit IVUpcoming Curriculum

Molecular Docking & In Silico Drug Design

Principles of molecular docking, receptor and ligand preparation, grid box definition, docking scoring functions (AutoDock Vina), and binding affinity evaluation.

Planned Topics:
Receptor & Ligand Preparation (PDBQT format)
Search Algorithms & Scoring Functions
AutoDock Vina Python Automation
Analyzing Hydrogen Bonds & Hydrophobic Interactions
Unit NotesContent in Roadmap

Syllabus units ready. Detailed materials will be published soon.

Unit VUpcoming Curriculum

Pharmacogenomics & Target Identification

Genomic variant analysis, Single Nucleotide Polymorphisms (SNPs) impacting drug metabolism (CYP450 enzymes), and drug-target interaction networks.

Planned Topics:
Pharmacogenomics Data Processing
CYP450 Enzyme Polymorphism Analytics
Network Pharmacology & Protein-Protein Interactions
In Silico Vaccine & Biotherapeutic Design
Unit NotesContent in Roadmap

Syllabus units ready. Detailed materials will be published soon.